- Salted & Roasted Nuts & Seeds Manufacturers, Tishomingo
- Salvage Yards, Tishomingo - Auto, Motorcycle, Boat, Trucks, etc
- Sand Gravel & Aggregate, Tishomingo
- Sandwich Shop Restaurants, Tishomingo
- Scientific & Laboratory Equipment & Instruments, Tishomingo
- Seafood Restaurants, Tishomingo
- Secondary Schools, Tishomingo
- Seeds & Bulbs Wholesale & Growers, Tishomingo
- Sheriff's Department, Tishomingo
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- Shoe Store - More, Tishomingo
- Shopping & Shopping Services, Tishomingo
- Signs, Tishomingo
- Social Services & Welfare, Tishomingo
- Spare Rib Restaurants, Tishomingo
- Specialty Stores, Tishomingo
- Sporting Goods Stores, Tishomingo
- Sports Medicine, Tishomingo - Doctors, Physicians & Surgeons
- State Government, Tishomingo
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